Prediabetes - Preventable Diabetes

Diposting oleh suzanna on Senin, 18 Mei 2015

 Prediabetes - Preventable Diabetes

Prediabetes - Preventable Diabetes
Diabetes has expanded the proportion of pandemic. It is estimated that 8.3% of the us population, or 25.8 million people have diabetes. About 95% of these have type 2 diabetes. Diabetes is the leading cause of limb amputation, kidney and new onset of blindness in American adults. People with diabetes are more likely than those without diabetes to develop and die from diseases of the heart and blood vessels, called cardiovascular disease. Adults with diabetes have heart disease death rates about two to four times higher than adults without diabetes. The risk for stroke two to four times higher among people with diabetes.
Prediabetes refers to the metabolic State intermediate between normal glucose homeostasis and diabetes. The term was first introduced in 1979 to replace the diabetes ' limit '. Pre-diabetes is becoming more common and more recognized in the United States. The u.s. Department of Health and Human Services estimates that 79 million Americans have prediabetes in 2007. It is estimated that 314 million people around the world have prediabetes, and the number is projected to increase to 418 million in the year 2025.

Diagnosis of Prediabetes

prediabetes diagnosis can be made in some way

Fasting Blood Glucose Test The patient must not eat anything for 24 hours period, and a blood glucose reading is then taken. If the reading is between 99 and 126mg/L (5.5 and 7 mmol/L) the patient has confirmed prediabetes.

Oral glucose tolerance test
involves measuring blood sugar levels two hours after drinking a glucose standard solution. If the reading is between 140 and 200 mg/L (7.8 and 11.1 mmol/L) prediabetes confirmed.

A random blood glucose test
if your blood glucose levels 140mg/L (7.8 mmol/L) at any time, this is an indication of insulin resistance, and fasting blood glucose tests warrants or the oral glucose tolerance test to confirm the diagnosis.

How do you treat? Call for early treatment of prediabetes is grabbing the momentum. Some recent studies have evaluated the role of lifestyle changes and medications for treatment of this disease:

  • How do you treat? Call for early treatment of prediabetes is grabbing the momentum. Some recent studies have evaluated the role of lifestyle changes and medications for treatment of this disease:
  • exercise: regular physical activity prevent progression to diabetes. At Da Qing IGT and Diabetes Study 110,660 men and women in China (Diabetes Care 1997; 20: 537-44.), development of diabetes fell from 67.7% to 41.1%, when comparing a group of control for group exercise conducted for 6 years.
  • diet: in a study in Finland (N Engl J Med 2001; 344: 1343-50), there are incidents of 23% of the development of the diabetes in the control group compared to only 11% in the intervention group for 4 years. Interventions aimed at reducing weight by 5% or more, reducing dietary fat to less than 30% of the total caloric intake and increase fiber to at least 15 grams per 1,000 calories consumed.
  • in a large study involving 27 clinical centers around the u.s. (N Eng J Med, February 7, 2002), 3234 prediabetic overweight participants were divided into two groups. One group received intensive training in diet, physical activity, and behavior modification. The goal is to reduce weight and maintain the loss 7%, and 150 minutes of exercise a week. The two groups that received metformin 850 mg twice a day. At the end of the study, the lifestyle intervention group reduced progression to diabetes by 58% compared to 31% in the metformin group.
  • a prediabetes task force (American Association of Clinical Endocrinologists 18 annual meeting, Houston, Tx. 2009) suggest a more aggressive therapeutic approach for these patients, recommends treating individuals with high risk of diabetes drugs such as metformin, acarbose, glucagon-like peptide 1 GnRH and thiazolidinediones. This treatment is not yet FDA approved for prediabetes, but supported by a strong scientific data indicate that early insulin resistance fight to protect and prevent the development of pancreas to diabetes.

Treatment and prevention of Prediabetes 

To prevent the onset of type 2 diabetes, maintain the function of Your beta cells and delaying the microvascular and cardiovascular complications associated with the disease, the patient was given the same advice prediabetic given to actual diabetes. Obesity is a big factor, therefore, exercise and weight loss are the main focus.
 Lifestyle interventions such as these have been found to provide the greatest benefit in preventing the progression to type 2 diabetes:
  1. Eating a healthy balanced diet low in salt.
  2. Physical exercise, between 30 to 60 minutes, at least five times per week.
  3. Reducing your weight, by even 5-10%, has a major impact on fat mass, blood pressure, and blood glucose.
  4. Studies have shown that a low-carb diet is a valuable prevention method in both diabetes and prediabetes.

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Gestational Diabetes - Prediabetes

Diposting oleh suzanna on Minggu, 17 Mei 2015

Gestational Diabetes - Prediabetes

Gestational Diabetes - Prediabetes
Gestational diabetes develops during pregnancy . Like other types of diabetes, gestational diabetes affects how your cells use sugar . Gestational diabetes causes high blood sugar that can affect your pregnancy and your baby's health.

Any pregnancy complication is concerning, but there's good news. Expectant moms can help control gestational diabetes by eating healthy foods, exercising and, if necessary, taking medication. Controlling blood sugar can prevent a difficult birth and keep you and your baby healthy.

In gestational diabetes, blood sugar usually returns to normal soon after delivery. But if you've had gestational diabetes, you're at risk for type 2 diabetes. You'll continue working with your health care team to monitor and manage your blood sugar.

During pregnancy – usually around the 24th week – many women develop gestational diabetes. A diagnosis of gestational diabetes doesn't mean that you had diabetes before you conceived, or that you will have diabetes after giving birth. But it's important to follow your doctor's advice regarding blood glucose (blood sugar) levels while you're planning your pregnancy, so you and your baby both remain healthy.

Gestational diabetes berkembang selama kehamilan (kehamilan). Seperti jenis lain dari diabetes, gestational diabetes mempengaruhi bagaimana sel-sel Anda menggunakan gula (glukosa). Gestational diabetes menyebabkan gula darah tinggi yang dapat mempengaruhi kehamilan Anda dan kesehatan bayi Anda. Komplikasi kehamilan apapun adalah tentang, tapi ada kabar baik. Ibu hamil dapat membantu kontrol diabetes gestational dengan makan makanan sehat, berolahraga dan, jika perlu, mengambil obat. Mengendalikan gula darah dapat mencegah kelahiran yang sulit dan menjaga Anda dan bayi Anda sehat. Pada gestational diabetes, gula darah biasanya kembali normal segera setelah pengiriman. Tapi jika Anda memiliki gestational diabetes, Anda berada pada risiko untuk diabetes tipe 2. Anda akan terus bekerja dengan tim perawatan kesehatan Anda untuk memantau dan mengelola gula darah Anda

Prediabetes

Prediabetes is "pre-existing diagnosis" diabetes — you can think of it as a warning sign. It is when your blood glucose levels (blood sugar level) higher than normal, but it was not high enough to be considered diabetes.

If you have prediabetes, you are at high risk of developing type 2 diabetes and also are at increased risk of developing heart disease. Prediabetes is a condition in which blood glucose levels are higher than normal, but not high enough to be classified as full-blown diabetes.

First, let's define what "prediabetes" and no. Diabetes is defined as having a blood plasma fasting glucose levels 126 mg/dl or higher on two separate occasions. If there are symptoms of diabetes and you have casual blood glucose is taken at a time that is equal to or greater than 200 mg/dl, and a second test showed high blood glucose levels are the same, then you have diabetes.

Prediabetes, type 2 diabetes and heart disease can be prevented by making lifestyle changes,

Weight loss:  helps the insulin your body makes to work better and lower your blood glucose levels.
 Physical activity:  it is important to do regular moderate physical activity to help manage your weight, and   reduce your blood glucose, blood pressure and cholesterol levels. Exercise also makes your insulin work better.
 A healthy diet:  this involves less fat, especially saturated fats, and more fruit, vegetables and high-fibre wholegrain foods.
 Stopping smoking:  smoking causes insulin resistance and increases the risk of blood vessel disease.
 Blood pressure and cholesterol control – these should be kept under control and checked regularly.

Gestational Prediabetes

Women with gestational diabetes mellitus (GDM) have higher rates of foetal macrosomia, shoulder dystocia and pregnancy-induced hypertension, and are at higher risk of developing type 2 diabetes. Herein, we introduce a new conceptual term, "gestational prediabetes", which requires the absence of diabetes before pregnancy, and the presence of blood glucose levels (or a related marker) in early pregnancy that are higher than normal, but not yet high enough to meet the diagnostic criteria for GDM. Identifying women with gestational prediabetes might be done in early pregnancy (e.g., 12 weeks' gestation) using conventional glycaemic testing, assessment of visceral abdominal adiposity or hepatic fat by ultrasonography, or measuring serum sex hormone-binding globulin or adiponectin. However, none of these approaches has been systematically compared to conventional predictors, such as maternal body mass index or waist circumference. Any early-pregnancy predictor of gestational prediabetes risk needs to have low cost, ease of administration, and a short turnaround time. The theoretical advantage of identifying women with gestational prediabetes would be to "prevent" the onset of GDM (and its inherent risks to the pregnancy) in a timelier manner. One sensible starting point would be an intervention to prevent early excessive weight gain in pregnancy, which is currently being evaluated by two randomized clinical trials. In addition, early intervention could offset the need for resource-intense GDM management or insulin therapy.

if you have prediabetes and you are Gestational, you are at risk for gestational diabetes. Gestational diabetes is diabetes that is first diagnosed during pregnancy.

Pregnancy is a stressful time for your body. In gestational diabetes, hormones from the placenta contributed to insulin resistance, which reduces the ability of insulin to regulate blood sugar levels. Your pancreas makes insulin, which does not produce enough insulin to overcome this resistance, so the glucose can't get into the cells for energy supplies and build for abnormal levels in the blood.

Gestational diabetes can affect you and your baby. This increases your risk of developing type 2 diabetes after delivery of your baby, and can affect the size of your baby, so it's more likely you'll have a baby that is too large for the labor. Having gestational diabetes also can put your baby at risk for low blood sugar levels at birth. However, there are things you can do to help prevent or delay the onset of diabetes or prediabetes, even after gestational diabetes. Diabetes Prevention Program (DPP) study found that moderate exercise and weight loss diet with low fat, low calorie diet helps delay or prevent the onset of type 2 diabetes even in patients at high risk, including people with a history of gestational diabetes. Prediabetes: what does it mean for you? Just because you have been diagnosed with prediabetes doesn't mean that you'll get gestational diabetes or type 2 diabetes progression. People with prediabetes can reduce their blood sugar levels to normal values and reduces the risk for developing diabetes. If you have prediabetes, here are some things you can do to help achieve a healthy blood glucose levels and decrease your risk of developing gestational diabetes.

Gestational Diabetes- Prediabetes

Just because you have been diagnosed with prediabetes does not mean that you will get gestational diabetes or progress to type 2 diabetes. People with prediabetes can reduce their blood glucose levels to normal values and reduce their risk for developing diabetes.

If you have prediabetes, here are some things you can do to help achieve a healthy blood glucose level and lower your risk of developing gestational diabetes.

  • Plan your pregnancy. It's important to talk with your doctor if you are planning a family — and follow your  doctor’s recommendations for getting healthier before the pregnancy.
  • Lifestyle modification. Lifestyle modification involves changing things you do in your everyday life to help improve your health. In the DPP study, lifestyle changes that included a low-fat diet and moderate exercise lowered the risk of developing diabetes by 58 percent over three years. Of course, smoking cessation and refraining from drinking alcohol are also critical to your health and the health of your baby.
  • Get some support. There is no need to go it alone. There are dietitians, nutritionists, and exercise counselors who can design a healthy diet and exercise regimen to help you reduce your risk of diabetes before, during, and after your pregnancy.
The medical community isn’t sure why some women develop gestational diabetes, although there are several risk factors that make it more likely that you will develop it:
  •  Age: Women over the age of 25 are more likely to get gestational diabetes.
  •  Weight: Women who are overweight (have a body mass index—or BMI—that’s above 25) are more at risk for gestational diabetes.
  •  Race/ethnicity: Gestational diabetes is more common within certain ethnic groups. African-Americans, Native Americans, Asian Americans, Hispanic people, and Pacific Islanders are more likely to have gestational diabetes.
  •  Family history: If someone else in your family has or had diabetes (type 1, type 2, or gestational diabetes), you’re at higher risk.
  •  Pre-diabetes: This is a “pre-diagnosis” of diabetes. It means that your blood glucose levels are elevated, but they aren’t high enough to be considered diabetes yet. If you’ve been told that you have pre-diabetes, you’re more likely to develop gestational diabetes.
  •  Previous pregnancies with gestational diabetes: If you developed gestational diabetes during another pregnancy, you’re more at risk for developing it again.









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